Differentiation of tomato races 1 and 2 of Verticillium dahliae using vegetative compatibility analysis

Vegetative or heterokaryon compatibility analysis has been a useful tool in studying genetic diversity in populations of many phytopathogenic fungi. The existence of a vegetative compatibility system in Verticillium dahliae identical to those operating in other ascomycetes and imperfect fungi has been demonstrated (2).

In this preliminary study, sixteen strains of V. dahliae designated as either tomato races 1 or 2 were tested for vegetative compatibility (Table 1). Compatibility was assessed by pairings of complementary nitrate-nonutilizing (nit) mutants. Nit mutants were induced from wild-type strains as follows. Agar-disks were cut from the edge of each wild-type strain of V. dahliae growing on minimal medium agar (MM) (1), and transferred to plates (4 disks/plate) containing corn meal agar with dextrose (Difco) amended with 25 g/L of potassium chlorate. After 8-12 days at 22-26 C, plates were inspected for fast growing fan-like chlorate-resistant sectors. When subcultured onto MM, sectors usually exhibited a sparse but expansive colony morphology in contrast to the dense mycelial growth of the wild type. All colonies showing a thin mycelial growth response on MM were referred to as nit mutants. Two phenotypically distinct nit mutants (nitl and nitM) were identified by growth tests on MM containing one of several nitrogen sources (1) from tester strains previously assigned to VCG's by Puhalla and Hummel (2). The following strains from their collection were used: V-44 and T-9 (VCG 1), WM and PH (VCG 2), 115 (VCG 3), and BB (VCG 4). In addition, Ohio strains S-92 (VCG 3) and S-39 (VCG 4) were employed. Vegetative compatibility was assessed by pairings of nit mutants derived from each tomato strain with nit mutants of tester strains. A nit mutant of each tomato strain was placed in the center of a plate containing MM. Two phenotypically distinct nit mutants of each tester strain of each VCG were plated 1.0-1.5 cm apart to either side. After 21-day incubation, strains were considered vegetatively compatible when heterokaryons were produced between the respective nit mutants as evidenced by the dense prototrophic growth at the line of mycelial contact. Preliminary results revealed that all 12 r ace 1 strains from Ohio, North Carolina, Japan, Canada and Australia were compatible with strains WM and PH (VCG 2) (Table 1). The remaining four race 2 strains from North Carolina and Australia were compatible primarily with S- 39 (VCG 4) and either compatible or partially-compatible with BB (VCG 4). If this trend proves to be consistent and since strains in 2 and 4 are highly incompatible, it would seem that vegetative compatibility analysis would be a useful tool to separate races 1 and 2 without resorting to the laborious and time consuming pathogenicity tests.

Table 1. Strains of Verticillium dahliae used in this study.

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Strain       Host plant Geographical origin  Donor^a  Assigned
designation  of origin    State Country                 VCG^b 
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395       Tomato (Race 1)  OH   U.S.A.          1         2
425       Tomato (Race 1)  OH   U.S.A.          1         2
442       Tomato (Race 1)  OH   U.S.A.          1         2
443       Tomato (Race 1)  OH   U.S.A.          1         2
450       Tomato (Race 1)  OH   U.S.A.          1         2
461       Tomato (Race 1)  OH   U.S.A.          1         2
410       Tomato (Race 1)  OH   U.S.A.          1         2
20-B      Tomato (Race 1)  NC   U.S.A.          2         2
TC        Tomato (Race 1)  --   Canada          3         2
77-10C    Tomato (Race 1)  --   Australia       4         2
58        Tomato (Race 1)  --   Australia       4         2
LE-8601   Tomato (Race 1)  --   Japan           5         2
RG#2      Tomato (Race 2)  NC   U.S.A.          2         4
RGG       Tomato (Race 2)  NC   U.S.A.          2         4
2011      Tomato (Race 2)  --   Australia       4         4
1035      Tomato (Race 2)  --   Australia       4         4
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a Isolate furnished courtesy of: 1 = R.C. Rowe, Ohio; 2 = P.B. Shoemaker, North Carolina; 3 = J.E. Puhalla, California; 4 = R.G. O'Brien, Australia; 5 = T. Iijima, Japan.

b VCG = vegetative compatibility group.

Literature Cited:

Correll, J. C., Klittich, C. J. R., and Leslie, J. F. 1987. Nitrate nonutilizing mutants of Fusarium oxysporum and their use in vegetative compatibility tests. Phytopathology 77:1640-1646.

Puhalla, J. E., and Hummel, M. 1983. Vegetative compatibility groups within Verticillium dahliae. Phytopathology 73:1305-1308.